PRDM16 wt Allele

Human PRDM16 wild-type allele is located within 1p36.23-p33 and is approximately 369 kb in length. This allele, which encodes PR domain zinc finger protein 16, is involved in the modulation of both fat cell differentiation and gene transcription. A reciprocal translocation t(1;3)(p36;q21) of the gene and the RPN1 gene is associated with myelodysplastic syndrome and acute myeloid leukemia. (NCI Thesaurus)

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PRDM16 Gene

This gene plays a role in both transcriptional regulation and adipocyte differentiation.

PRDM1 wt Allele

Human PRDM1 wild-type allele is located within 6q21-q22.1 and is approximately 24 kb in length. This allele, which encodes PR domain zinc…

PRDM1 Gene

This gene is involved in repression of transcription. It plays a role in the formation of pre-plasma memory B cells and immunoglobulin-secreting…

PRCC/TFE3 Fusion Protein

A fusion protein encoded by the PRCC/TFE3 fusion gene. This protein is comprised of the N-terminal proline/leucine/glycine rich domain of proline-rich protein…

PRCC/TFE3 Fusion Gene

A fusion gene that results from a chromosomal translocation t(X;1)(p11.2;q21.2) which fuses the 5' half of the PRCC gene to exon 2…

PRCC wt Allele

Human PRCC wild-type allele is located in the vicinity of 1q21.1 and is approximately 33 kb in length. This allele, which encodes…