Health / Medical Topics

    PRKAR1A/RARA Fusion Protein

    A fusion protein encoded by the PRKAR1A/RARA fusion gene. This protein is comprised of the N-terminal protein dimerization domain of the cAMP-dependent protein kinase type I-alpha regulatory subunit protein fused to the C-terminal DNA and ligand binding domains of the retinoic acid receptor alpha protein. (NCI Thesaurus)




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    A fusion gene that results from a cryptic rearrangement of chromosome 17 which fuses the first 100 nucleotides of exon 3 of…
    Human PRKAR1A wild-type allele is located within 17q23-q24 and is approximately 21 kb in length. This allele, which encodes cAMP-dependent protein kinase…
    This gene plays a role in the regulation of protein kinase A.
    Human PRKACG wild-type allele is located within 9q13 and is approximately 2 kb in length. This allele, which encodes cAMP-dependent protein kinase,…
    This gene is involved in brain memory function, spermatogenesis and male gonad development.
    Human PRKACB wild-type allele is located in the vicinity of 1p36.1 and is approximately 160 kb in length. This allele, which encodes…

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