Health / Medical Topics

    PRKAR1A/RET Fusion Gene

    A fusion gene that results from a chromosomal translocation t(10;17)(q11.2;q23) which fuses 717 nucleotides of the PRKAR1A gene and the 3' portion of the RET gene. This rearrangement is associated with papillary thyroid carcinoma. (NCI Thesaurus)




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    Human PRKAR1A wild-type allele is located within 17q23-q24 and is approximately 21 kb in length. This allele, which encodes cAMP-dependent protein kinase…
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