Prolia

Pronunciation

A drug used to prevent or treat certain bone problems. Under the brand name Xgeva, it is used to prevent broken bones and other bone problems caused by solid tumors that have spread to bone. It is also used in certain patients to treat giant cell tumor of the bone that cannot be removed by surgery. Under the brand name Prolia, it is used to treat osteoporosis (a decrease in bone mass and density) in postmenopausal women who have a high risk of breaking bones. Prolia is also being studied in the treatment of other conditions and types of cancer. It binds to a protein called RANKL, which keeps RANKL from binding to another protein called RANK on the surface of certain bone cells, including bone cancer cells. This may help keep bone from breaking down and cancer cells from growing. Prolia is a type of monoclonal antibody. Also called AMG 162, denosumab, and Xgeva. (NCI Dictionary)

YOU MAY ALSO LIKE

Proleukin

A drug used to treat some types of cancer. It is a form of interleukin-2, a cytokine made by leukocytes (white blood…

Prolate

A spherical shape that has a polar diameter that is longer than its equatorial diameter.

Prolactin-Producing Pituitary Gland Neoplasm

An adenoma or carcinoma of the anterior lobe of the pituitary gland that produces prolactin.

Prolactin-Producing Pituitary Gland Carcinoma

A rare, hormonally functioning or non-functioning pituitary gland adenocarcinoma that produces prolactin.

Prolactin-Producing Pituitary Gland Adenoma

An adenoma of the anterior lobe of the pituitary gland that produces prolactin. It is the most common type of pituitary…

Prolactin-Inducible Protein

Prolactin-inducible protein (146 aa, ~17 kDa) is encoded by the human PIP gene. This protein plays a role in ligand binding. …