Propacetamol

A water-soluble para-aminophenol derivative and ester prodrug of acetaminophen in which acetaminophen is bound to the carboxylic acid diethylglycine, with analgesic and antipyretic activities. Upon intravenous administration, propacetamol is hydrolyzed by plasma esterases into its active form acetaminophen. Although the exact mechanism of action has yet to be fully elucidated despite its widespread use, acetaminophen enters the central nervous system and acts centrally. This agent binds to cyclooxygenase (COX) and prevents the metabolism of arachidonic acid to prostaglandin. A reduction in prostaglandin formation relieves pain and reduces fever. Acetaminophen may also act centrally on cannabinoid receptors and on N-methyl-D-aspartate (NMDA) receptors. (NCI Thesaurus)

YOU MAY ALSO LIKE

Pronounced Dead

The status of an individual is officially declared not living by an authority.

Pronormoblast to Total Cell Ratio Measurement

The determination of the ratio of pronormoblasts compared to total cells present in a sample. The measurement may be expressed as a…

Prong Device Component

Any pointed projection on a device, usually one designed to attach a device to something else.

Proneural Glioblastoma

A molecular subtype of glioblastoma that is associated with younger age at presentation and is characterized by p53 mutations and PDGFRa…

Prone Position

An anterior recumbent body position whereby the person lies on its stomach and faces downward.

Promyelocytic leukemia

An aggressive (fast-growing) type of acute myeloid leukemia in which there are too many immature blood-forming cells in the blood and bone…