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protein kinase B
Pronunciation
Definition 1
A group of enzymes involved in several processes related to cell growth and survival. Protein kinase B enzymes help to transfer signals inside cells. A protein kinase B enzyme is a type of serine/threonine protein kinase. Also called Akt. (NCI Dictionary)
Definition 2
Expressed in diverse tissues, Protein Kinase B (AKT/RAC Family) is a group (Alpha, Beta and Gamma) of cytoplasmic serine/threonine enzymes that covalently transfer the terminal, gamma phosphate group from ATP to a variety of substrate proteins and regulate cell signaling responses to insulin, PDGF, and IGF1 (through PI3K) involved in cell survival, cell proliferation, differentiation, apoptosis, glycogen synthesis, and glucose uptake. (NCI Thesaurus)
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