Health / Medical Topics |
PSENEN wt Allele
Human PSENEN wild-type allele is located in the vicinity of 19q13.12 and is approximately 1 kb in length. This allele, which encodes gamma-secretase subunit PEN-2 protein, is involved in the regulation of both Notch-dependent signaling and intramembrane proteolysis. (NCI Thesaurus)
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This gene plays a role in the regulation of both gamma-secretase activity and Notch signaling pathways.
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