| Health / Medical Topics |
PTEN Gene Inactivation
A molecular genetic abnormality indicating the presence of an inactivating mutation in the PTEN gene on chromosome 10q23. (NCI Thesaurus)
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This gene plays a role in signal transduction and apoptosis. It is also involved in the regulation of cell cycle progression. …
A protein that helps control many cell functions, including cell division and cell death. Mutations (changes) in the gene that makes PTEN…
Human PTCH2 wild-type allele is located within 1p33-p34 and is approximately 21 kb in length. This allele, which encodes protein patched homolog…
This gene plays a role in intercellular communication, embryonic structure development, and in tumorigenesis.
Human PTCH1 wild-type allele is located in the vicinity of 9q22.3 and is approximately 65 kb in length. This allele, which encodes…
This gene is involved in tumor suppression and mutations in this gene have been associated with several cancers and cancer related…
