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Pteropterin
A crystalline conjugate of folic acid, having general properties of a polypeptide. Pteropterin differs from folic acid in that it consists of three molecules of glutamic acid instead of one. Pteropterin can potentially be used as an antimetabolite in the treatment of cancer. (NCI Thesaurus)
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Folic acid analogs containing a pteridine base, a two-ring heterocyclic aromatic compound, and are used to interfere with folic acid.
PTEN is a tumor suppressor gene. Recombinant PTEN is capable of dephosphorylating phosphatidylinositol 3,4,5-triphosphate[PI(3,4,5)P3], the product of phosphatidylinositol 3-kinase. Many of the…
Human PTEN wild type allele is located in the vicinity of 10q23.3 and is approximately 109 kb in length. This allele, which…
A protein that helps control many cell functions, including cell division and cell death. Mutations (changes) in the gene that makes PTEN…
A molecular abnormality referring to the loss of at least one copy of the PTEN gene (10q23).
A molecular genetic abnormality indicating the presence of an inactivating mutation in the PTEN gene on chromosome 10q23.
