PTPN11 wt Allele

Human PTPN11 wild-type allele is located within 12q24 and is approximately 91 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 11 protein, is involved in the dephosphorylation of protein-tyrosine phosphates. The PTPN11 gene is associated with severe congenital neutropenia as well as several forms of leukemia. (NCI Thesaurus)

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PTPN11 Gene Mutation

Mutation of the protein tyrosine phosphatase, non-receptor type 11 gene. It is seen in cases of juvenile myelomonocytic leukemia.

PTPN11 Gene

This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and…

PTPN1 wt Allele

Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…

PTPN1 Gene

This gene plays a role in the regulation of insulin signaling and inhibition of cell growth.

PTP4A1 wt Allele

Human PTP4A1 wild-type allele is located within 6q12 and is approximately 11 kb in length. This allele, which encodes protein tyrosine phosphatase…

PTP4A1 Gene

This gene is involved in liver cell growth and the cellular response to mitogens.