PTPN12 wt Allele

Human PTPN12 wild-type allele is located in the vicinity of 7q11.23 and is approximately 103 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 12 protein, plays a role in the dephosphorylation of protein-tyrosine phosphates. Defects in the PTPN12 gene are associated with colon cancer. (NCI Thesaurus)

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PTPN12 Gene

This gene plays a role in the regulation of cell shape and mobility.

PTPN11 wt Allele

Human PTPN11 wild-type allele is located within 12q24 and is approximately 91 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…

PTPN11 Gene Mutation

Mutation of the protein tyrosine phosphatase, non-receptor type 11 gene. It is seen in cases of juvenile myelomonocytic leukemia.

PTPN11 Gene

This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and…

PTPN1 wt Allele

Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…

PTPN1 Gene

This gene plays a role in the regulation of insulin signaling and inhibition of cell growth.