PTPN6 wt Allele

Human PTPN6 wild-type allele is located within 12p13 and is approximately 29 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 6 protein, is involved in the dephosphorylation of protein-tyrosine phosphates. Aberrant methylation of the PTPN6 gene results in low expression levels in leukemias and lymphomas. (NCI Thesaurus)

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PTPN6 Gene

This gene plays a role in the regulation of multiple signaling pathways in hematopoietic cells.

PTPN22 wt Allele

Human PTPN22 wild-type allele is located within 1p13.3-p13.1 and is approximately 123 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…

PTPN22 Gene

This gene plays a role in the regulation of the immune system, the development of autoimmunity and the cellular response to…

PTPN13 wt Allele

Human PTPN13 wild-type allele is located in the vicinity of 4q21.3 and is approximately 221 kb in length. This allele, which encodes…

PTPN13 Gene

This gene is involved in both protein dephosphorylation and signal transduction.

PTPN12 wt Allele

Human PTPN12 wild-type allele is located in the vicinity of 7q11.23 and is approximately 103 kb in length. This allele, which encodes…