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Purinergic Receptor
Definition 1
Cell surface proteins that bind purines with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized classes of purinergic receptors in mammals are the P1 receptors, which prefer adenosine, and the P2 receptors, which prefer ATP or ADP. (NCI Thesaurus)
Definition 2
any molecular receptor for adenine, guanine, or other purine, or their nucleosides or nucleotides, including cyclic nucleotides other than cAMP (see NT); adenine and ATP are important neurotransmitters, so their receptors are found in neural synapses, among other sites. (NIH CRISP Thesaurus)
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One of the purinergic P1 receptors that prefers adenosine to other endogenous purines.
PNP reversibly catalyzes the phosphorolysis of the purine nucleosides, (deoxy)inosine and (deoxy)guanosine, to their respective purine bases and the corresponding ribose-1-phosphate. …
Purine Synthesis Inhibition involves interference with, or restraint of, the activities of biologic molecules or complexes involved in the enzymatic formation of…
Any substance that inhibits purine nucleoside phosphorylase, an enzyme involved in the purine salvage pathway that metabolizes adenosine into adenine, inosine into…
Purine nucleoside phosphorylase (289 aa, ~32 kDa) is encoded by the human PNP gene. This protein plays a role in purine…
An antimetabolite that affects the metabolism and utilization of purines.
