Health / Medical Topics |
Rabeprazole Sodium
The sodium salt of the prodrug rabeprazole, a substituted benzimidazole proton pump inhibitor, with potential anti-ulcer activity. After protonation, accumulation, and transformation to the active sulfenamide within the acidic environment of gastric parietal cells, rabeprazole selectively and irreversibly binds to and inhibits the H+, K+ATPase (hydrogen-potassium adenosine triphosphatase) enzyme system located on the parietal cell secretory surface, inhibiting gastric acid secretion. (NCI Thesaurus)
YOU MAY ALSO LIKE
An alpha-pyridylmethylsulfinyl benzimidazole and a selective and irreversible proton pump inhibitor with antisecretory property. Rabeprazole enters the parietal cell and accumulates in…
A fusion protein (1318, ~150 kDa) encoded by the RABEP1/PDGFRB fusion gene. This protein is comprised of 85% of the Rab GTPase-binding…
A fusion gene that results from a chromosomal translocation t(5;17)(q33;p13) which fuses most of the RABEP1 gene with the 3' part of…
Human RABEP1 wild-type allele is located in the vicinity of 17p13.2 and is approximately 104 kb in length. This allele, which encodes…
This gene is involved in the regulation of both GTPase activity and endocytosis.
Various members of the family Leporidae, especially those of the genus Sylvilagus.