Health / Medical Topics |
RAD51B/HMGA2 Fusion Gene
A fusion gene that results from a chromosomal translocation t(12;14)(q14-15;q22-24) which fuses exon 5, 7, 9 or 10 of the RAD51B gene to exon 2, 4 or 5 of the HMGA2 gene. This rearrangement is associated with uterine leiomyoma. (NCI Thesaurus)
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Human RAD51B wild-type allele is located within 14q23-q24.2 and is approximately 776 kb in length. This allele, which encodes DNA repair protein…
This gene plays a role in the mediation of homologous recombinational repair of DNA.
Human RAD51 wild-type allele is located in the vicinity of 15q15.1 and is approximately 37 kb in length. This allele, which encodes…
Encoded by human RAD51C Gene (RECA Family, RAD51 Subfamily), the 376-amino acid 42 kD RAD51 Homolog C is a probable nuclear protein…
This gene is involved in both homologous recombination and repair of DNA.
The RAD51 family of related genes, identified in both yeast and humans, encode strand-transfer proteins thought to be involved in recombinational repair…