RAD54B Homolog

Highly expressed in testis and spleen by human RAD54B Gene (SNF2/SWI2 Family), the two isoforms of 910-aa 100-kD nucleoplasmic RAD54B Homolog exhibit significant homology to RAD54 and motifs similar to DNA and RNA helicases. RAD54B binds to double-stranded DNA and displays DNA-associated ATPase activity. RAD54B appears to associate indirectly with RAD51 through its N-terminal domain and may colocalize with RAD54 and BRCA1. Part of a complex involved in meiotic and mitotic homologous DNA recombination repair, RAD54B plays a critical role in targeted integration and recombination in concert with other RAD52 epistasis group members without affecting cell growth, sensitivity to DNA damaging agents, or sister chromatid exchange. (NCI Thesaurus)

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RAD54B Gene

This gene plays a role in DNA repair and mitotic/meiotic recombination.

RAD54-Like Protein

RAD54-Like Protein (RAD54L), encoded by the RAD54L gene, belongs to the DEAD-like helicase superfamily. RAD54L plays a role in homologous recombination related…

RAD52 wt Allele

Human RAD52 wild-type allele is located within 12p13-p12.2 and is approximately 79 kb in length. This allele, which encodes DNA repair protein…

RAD52 Gene

This gene is involved in both double-strand break repair and homologous recombination.

RAD51C wt Allele

Human RAD51C wild-type allele is located within 17q22-q23 and is approximately 3 kb in length. This allele, which encodes DNA repair protein…

RAD51C Gene

This gene plays a role in DNA repair and meiotic recombination.