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RADIOTHERAPY
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
(medicine) the treatment of disease (especially cancer) by exposure to a radioactive substance
Synonyms:
actinotherapy; irradiation; radiation; radiation therapy; radiotherapy
Classified under:
Nouns denoting acts or actions
Hypernyms ("radiotherapy" is a kind of...):
therapy ((medicine) the act of caring for someone (as by medication or remedial training etc.))
Domain category:
medical specialty; medicine (the branches of medical science that deal with nonsurgical techniques)
Hyponyms (each of the following is a kind of "radiotherapy"):
phototherapy (the use of strong light to treat acne or hyperbilirubinemia of the newborn)
Curietherapy; radium therapy (the use of radium in radiation therapy)
X-ray therapy (the therapeutic use of X rays)
Derivation:
radiotherapist (a medical specialist who uses radioactive substances and X-rays in the treatment of disease)
Context examples:
EXAMPLE(S): chemotherapy, radiotherapy, hormonal therapy, alternative therapy In the case where categoryCode = anti-cancer treatment, subcategoryCode may = radiotherapy, and nameCode may = external beam radiotherapy.
(Defined Activity Subcategory Code, NCI Thesaurus/BRIDG)
PARP 1/2 inhibitor E7449 may enhance the cytotoxicity of DNA-damaging agents and of radiotherapy.
(PARP 1/2 Inhibitor E7449, NCI Thesaurus)
In addition, AZD6738 sensitizes tumor cells to chemo- and radiotherapy.
(ATR Kinase Inhibitor AZD6738, NCI Thesaurus)
Dysregulation of the PI3K/Akt/mTOR pathway is frequently found in solid tumors and results in increased tumor cell growth, survival, and resistance to chemotherapy and radiotherapy.
(PI3K Alpha/Beta Inhibitor BAY1082439, NCI Thesaurus)
Dysregulation of the PI3K/Akt/mTOR pathway is frequently found in solid tumors and results in the promotion of tumor cell growth, survival, and resistance to both chemotherapy and radiotherapy.
(PI3K-beta Inhibitor GSK2636771, NCI Thesaurus)
Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy. mTOR is a serine/threonine kinase downstream of PI3K, which also has PI3K-independent activity.
(PI3K/mTOR Kinase Inhibitor VS-5584, NCI Thesaurus)
Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy.
(pan-PI3K/mTOR Inhibitor PQR309, NCI Thesaurus)
Agents used in Boron Neutron Capture Therapy, a type of radiotherapy, as boron (boron-10) carriers.
(Boron Delivery Agent, NCI Thesaurus)
Compared to standard radiotherapy, because of the inert nature of NBTXR3, this agent emits electrons only during its exposure to radiation which improves radiotherapy efficiency.
(Hafnium Oxide-containing Nanoparticles NBTXR3, NCI Thesaurus)
EXAMPLE(S): In the case where categoryCode = "anti-cancer treatment", the subcategoryCode may = "radiotherapy", and the nameCode may = "external beam radiotherapy".
(Defined Activity Category Code, NCI Thesaurus/BRIDG)