Randomization

Pronunciation

Definition 1

When referring to an experiment or clinical trial, the process by which animal or human subjects are assigned by chance to separate groups that compare different treatments or other interventions. Randomization gives each participant an equal chance of being assigned to any of the groups. (NCI Dictionary)

Definition 2

The allocation of individuals to groups by chance, especially in order to control the variables in an experiment. (NCI Thesaurus)

Definition 3

The process of assigning trial subjects to treatment or control groups using an element of chance to determine the assignments in order to reduce bias. NOTE: Unequal randomization is used to allocate subjects into groups at a differential rate; for example, three subjects may be assigned to a treatment group for every one assigned to the control group. [ICH E6 1.48] See also balanced study. (CDISC glossary) (NCI Thesaurus/CDISC)

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