| Health / Medical Topics |
RARB Gene
This gene is involved in the regulation of embryonic morphogenesis and related processes. (NCI Thesaurus)
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A fusion protein encoded by the RARA/ZBTB16 fusion gene. This protein is comprised of the N-terminal transcriptional activation domain of the retinoic…
A fusion gene that results from a chromosomal translocation t(11;17)(q23;q21) which fuses the exon 3 of the RARA gene to the 3'…
A fusion gene that results from a chromosomal translocation t(15;17)(q22;q21) which fuses the first 2 exons of the RARA gene with the…
Human RARA wild-type allele is located within 17q21 and is approximately 48 kb in length. This allele, which encodes retinoic acid receptor…
This gene plays a role in transcription and retinoic acid receptor signal transduction.
Once retinoids are bound by the RAR/RXR heterodimer they became transcriptional activated. As a consequence they are degraded by the proteasome. Phosphorylation…
