Health / Medical Topics

    Ras Protein Specific Guanine Nucleotide Releasing Factor 2

    Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form. RASGRF2 is able to activate both RAS and RAC, thereby coordinating the signaling of distinct MAP kinase cascades. (NCI Thesaurus)




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