Health / Medical Topics

    RASSF1 wt Allele

    Human RASSF1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 11 kb in length. This allele, which encodes ras association domain family 1 protein, is involved in DNA hypermethylation and DNA repair. The gene is also associated with the pathogenesis of a variety of cancers, and is considered to be a candidate tumor suppressor gene. (NCI Thesaurus)




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