Health / Medical Topics

    RBBP8 wt Allele

    Human RBBP8 wild-type allele is located in the vicinity of 18q11.2 and is approximately 93 kb in length. This allele, which encodes retinoblastoma binding protein 8, plays a role in the modulation of both the cell cycle and cellular proliferation and may be involved in tumor suppression. Missense mutations in the gene are associated with pancreatic carcinoma. (NCI Thesaurus)




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