RBM15/MKL1 Fusion Gene

A fusion gene that results from a chromosomal translocation t(1;22)(p13;q13) which fuses the 5' portion of the RBM15 gene to the 3' portion of the MKL1 gene. This rearrangement is associated with infantile acute megakaryoblastic leukemia. (NCI Thesaurus)

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RBM15 wt Allele

Human RBM15 wild-type allele is located in the vicinity of 1p13 and is approximately 8 kb in length. This allele, which encodes…

RBM15 Gene

This gene plays a role in RNA binding.

RBL2 wt Allele

Human RBL2 wild-type allele is located in the vicinity of 16q12.2 and is approximately 57 kb in length. This allele, which encodes…

RBL2 Gene

This gene is involved in transcriptional regulation and cellular proliferation.

RBL1 wt Allele

Human RBL1 wild-type allele is located in the vicinity of 20q11.2 and is approximately 100 kb in length. This allele, which encodes…

RBL1 Gene

This gene plays a role in cell cycle regulation.