Health / Medical Topics

    Receptor

    Pronunciation

    Definition 1

    A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific effect in the cell. (NCI Dictionary)

    Definition 2

    A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways. (NCI Thesaurus)




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