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Receptor Tyrosine-Protein Kinase erbB-2
Definition 1
Receptor tyrosine-protein kinase erbB-2 (1255 aa, ~138 kDa) is encoded by the human ERBB2 gene. This protein is involved in cell proliferation, tyrosine phosphorylation and signal transduction. (NCI Thesaurus)
Definition 2
A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer cells removed from the body may be tested for the presence of c-erbB-2 to help decide the best type of treatment. c-erbB-2 is a type of receptor tyrosine kinase. (NCI Dictionary)
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