| Health / Medical Topics |
Recombinant Flt3 Ligand
Definition 1
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine Flt3. Flt3 ligand binds to the Flt3 tyrosine kinase receptor and, synergistically with other growth factors, stimulates the proliferation and mobilization of bone marrow precursor cells, including CD34+ cells, and dendritic cells. When proteolytically cleaved, the transmembrane isoform of Flt3 ligand generates the soluble form soluble Flt3 ligand, which is also biologically active. (NCI Thesaurus)
Definition 2
A drug that increases the number of immune cells and may stimulate the immune system to kill cancer cells. (NCI Dictionary)
YOU MAY ALSO LIKE
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 7 (FGF-7). Because it stimulates proliferation…
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 6 (FGF-6). Because of the…
A recombinant form of the heparin-binding fibroblast growth factor 5 (FGF-5). FGF-5 may function as a growth factor during embryogenesis and…
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 4 (FGF-4). Therapeutic FGF-4 induces vascular…
A recombinant agent which is chemically identical to or similar to endogenous fibroblast growth factor 3 (FGF-3). FGF-3 is a growth factor…
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 2 (FGF-2). Reflecting its endogenous…
