Health / Medical Topics |
Recombinant Fowlpox-B7.1
A recombinant fowlpox virus vector encoding human B7.1 (CD80 antigen), a T-cell costimulatory molecule. Recombinant Fowlpox-B7.1 may be used as a vaccine vector; incorporating the B7-1 gene into this vector may enhance the presentation of fowlpox virus vector-encoded tumor antigens to antigen presenting cells (APC) and activate cytotoxic T-cells against tumor antigen-expressing tumors. The fowlpox vector is easily manipulated and does not multiply in human tissues. (NCI Thesaurus)
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