| Health / Medical Topics |
Recombinant Interleukin-14
A recombinant peptide, which is chemically identical or similar to the endogenous cytokine interleukin-14 (IL-14). The cytokine inhibits immunoglobulin secretion and selectively expands activated B-cell subpopulations. An IL-14 receptor is found on activated B-cells, but not in resting B-cells. This agent is unrelated to other cytokines but has homology with complement factor Bb. Autocrine or paracrine production of IL-14 may play a significant role in the rapid proliferation of aggressive non-Hodgkin's lymphoma (NHL-B). Interrupting this pathway could be a useful goal of therapy for patients resistant to conventional chemotherapy. (NCI Thesaurus)
YOU MAY ALSO LIKE
The recombinant analogue of an endogenous cytokine interleukin 13 with potential antineoplastic activity. Produced by lymphocytes and exhibiting a variety of functions,…
A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface…
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine interleukin 1 (IL-1)-beta. Produced by monocytes…
A recombinant agent which is chemically identical to or similar to the endogenous protein cytokine interleukin-1 (IL-1). The IL-1 precursor is produced…
Any of the recombinant form of the naturally occurring Interleukin-1 Receptor Antagonist that blocks the biological activity of Interleukin-1 by binding to…
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-1 (IL-1). Produced mainly by monocytes, endogenous…
