Health / Medical Topics |
Recombinant Prothymosin Alpha
A recombinant form of the endogenous polypeptide hormone that exerts immunomodulatory effects primarily on mononuclear cells. Prothymosin alpha stimulates the production of various cytokines including granulocyte/macrophage colony stimulating factor (GM-CSF) alpha, gamma interferon (IFN) and interleukins such as IL-2. This agent may also increase some tumor antigens expression, thus inducing better T lymphocyte responses to tumor cells. Combined with chemotherapy, prothymosin alpha may exhibit significant anti-tumor effects. This agent also helps to regenerate lymph node and bone marrow cells after treatment with certain toxic chemotherapeutics. (NCI Thesaurus)
YOU MAY ALSO LIKE
In vivo synthesis of recombinant proteins through recombinant DNA techniques, followed by purification.
Proteins produced by genes or recombinant DNA that has been artificially engineered and inserted into a heterologous host. Recombinant proteins are used…
A recombinant form of the human PRAME (Preferentially Expressed Antigen of Melanoma) protein combined with the AS15 adjuvant, with potential immunostimulatory and…
A recombinant form of the heparin-binding cytokine pleiotrophin. Developmentally regulated, pleiotrophin functions as a growth factor during embryogenesis and the neonatal…
Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif of eight…
A recombinant form of the endogenous chemokine platelet factor 4 with potential antiangiogenesis and antineoplastic activities. As a heparin-binding tetramer, recombinant platelet…