| Health / Medical Topics |
Recombinant RANTES
Definition 1
A member of the IL-8 superfamily of cytokines and released from platelets and activated T-cells, RANTES is a selective chemoattractant for eosinophils, monocytes, and T-lymphocytes. RANTES is one of the ligands for chemokine receptor CCR5. RANTES expression in peripheral lymphocytes increases exponentially following mitogenic or antigenic stimulation. RANTES is one of the major HIV-suppressive factors produced by CD8-positive T-cells. (NCI Thesaurus)
Definition 2
A chemokine that is a chemoattractant for eosinophils, monocytes, and lymphocytes. It is a potent and selective eosinophil chemotaxin that is stored in and released from platelets and activated T-cells. (NLM, Medical Subject Headings)
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