| Health / Medical Topics |
Regulator of G-Protein Signaling 1
Induced in response to several activation signals and encoded by B-cell specific immediate early human RGS1 Gene (RGS Family), 196-aa 22.5-kDa Regulator of G-Protein Signaling 1, containing 1 RGS domain, is likely involved in regulation of B-cell activation and proliferation. Potentially regulated by protein kinase(s), RGS1 inhibits signal transduction by increasing GTPase activity of G protein alpha subunits, driving them into the inactive GDP-bound form. (NCI Thesaurus)
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