RELA wt Allele

Human RELA wild-type allele is located in the vicinity of 11q13 and is approximately 9 kb in length. This allele, which encodes transcription factor p65 protein, plays a role in the modulation of transcription by RNA polymerase II. Infrequently, lymphoproliferative disorders are associated with the translocation t(11;14)(q14;q32) of this gene. Amplification or increased expression of this gene has also been noted in some cases of squamous carcinomas of the head and neck and adenocarcinomas of the breast and stomach. (NCI Thesaurus)

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RELA Pathway

The rel/NF-kB family of transcription factors regulates the activity of genes involved in the immune response, hematopoiesis, and inflammation. NF-kB is…

RELA Gene

This gene plays a role in transcriptional regulation and NFKB signal transduction.

REL wt Allele

Human REL wild-type allele is located within 2p13-p12 and is approximately 41 kb in length. This allele, which encodes C-Rel proto-oncogene protein,…

REL Gene

This gene is involved in transcriptional regulation and signal transduction through the nuclear factor kappa B NFKB signal transduction pathway.

Rejected

Having been judged unacceptable.

Reiter Syndrome

A rare, reactive inflammatory disorder seen following bacterial infection. It predominantly affects males aged 20-40. Individuals with HLA-B27 antigen are estimated to…