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Renal tubular acidosis
Pronunciation
Definition 1
A rare disorder in which structures in the kidney that filter the blood are impaired, producing urine that is more acid than normal. (NCI Dictionary)
Definition 2
Failure of the renal tubules of the kidney to excrete urine of normal acidity resulting in metabolic acidosis. It may lead to hypercalcinuria, nephrolithiasis, and renal failure. Causes include autoimmune disorders (e.g., Sjogren syndrome, systemic lupus erythematosus, and rheumatoid arthritis), medications (e.g., non steroidal anti-inflammatory drugs, diuretics, and blood pressure medications), Fanconi syndrome, or it may be familiar. (NCI Thesaurus)
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