Health / Medical Topics

    Restriction Fragment Length Polymorphism

    Variation occurring within a species in the length of DNA fragments generated by a specific endonuclease. Such variations are generated by mutations that create or abolish recognition sites for these enzymes. (NCI Thesaurus)




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    Use of restriction endonucleases to generate a physical map of genomes, genes, or other segments of DNA.
    The specific DNA base that is cut by a specific restriction enzyme.
    Identification of restriction enzyme sites in DNA samples or DNA sequences.
    Enzymes that exhibit endonuclease activity at a specific short nucleotide sequence to cleave strands of DNA.
    Anything that limits; a limitation.
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