| Health / Medical Topics |
Reticulon 1
Expressed in neural and neuroendocrine tissues by human RTN1 Gene (Reticulon Family), 3 isoforms (A, B, C) of Reticulon 1, with unique N termini, are localized to ER membranes and contain a reticulon domain and 2 large C-terminal hydrophobic domains. RTN1 may be involved in neuroendocrine secretion or membrane trafficking. RTN1-A is a 776-aa 135-kD Ser/Pro-rich protein that contains multiple potential phosphorylation sites; RTN1-B is 356-aa and RTN1-C is 208-aa. RTN1-A and RTN1-B are phosphorylated and expression of RTN1-C is strongly correlated with neuronal differentiation. (NCI Thesaurus)
YOU MAY ALSO LIKE
A widely distributed collection of both free and fixed macrophages derived from bone marrow precursor cells by way of monocytes; their substantial…
Hyperplasia of reticuloendothelial tissue, in any organ or tissue. A related concept is reticulosis which is an increase in reticuloendothelial elements. …
The determination of the ratio of reticulocytes compared to erythrocytes in a blood sample. The measurement may be expressed as a ratio…
The determination of the amount of hemoglobin in reticulocytes within a sample.
The determination of the number of reticulocytes in a blood sample.
Immature erythrocytes that have just undergone extrusion of their cell nucleus. They still contain some organelles that gradually decrease in number as…
