Library / English Dictionary

RETROVIRUS

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Any of a group of viruses that contain two single-strand linear RNA molecules per virion and reverse transcriptase (RNA to DNA); the virus transcribes its RNA into a cDNA provirus that is then incorporated into the host cell

Classified under:

Nouns denoting animals

Hypernyms ("retrovirus" is a kind of...):

animal virus (an animal pathogen that is a virus)

Hyponyms (each of the following is a kind of "retrovirus"):

HTLV-1; human T-cell leukemia virus-1 (retrovirus causing T-cell leukemia)

HIV; human immunodeficiency virus (the virus that causes acquired immune deficiency syndrome (AIDS); it replicates in and kills the helper T cells)

Credits

 Context examples: 

An rna-type retrovirus with a c-type morphology.

(Alpharetrovirus, NCI Thesaurus)

A genus of single-stranded, reverse-transcribing RNA retroviruses with type B or type C morphology.

(Betaretrovirus, NCI Thesaurus)

A species of avian type C retroviruses (RETROVIRUSES TYPE C, AVIAN) causing anemia in fowl.

(Avian Myeloblastosis Virus, NLM, Medical Subject Headings)

Allodepleted haploidentical T-lymphocytes transduced with the Gal-V pseudotyped retrovirus vector encoding SFG.iCasp9-2A-deltaCD19, with potential immune reconstitution property.

(Allodepleted Haploidentical T Cells-expressing Inducible Caspase 9, NCI Thesaurus)

This allele, which encodes murine retrovirus integration site 1 homolog protein, plays a role in the regulation of both nitric oxide signaling and calcium release.

(MRVI1 wt Allele, NCI Thesaurus)

A murine retrovirus containing human PDGFB cDNA may be used to induce brain tumors in animal models of brain tumorigenesis.

(Murine Retrovirus Containing Human PDGFB cDNA, NCI Thesaurus)

Treatment with drugs that inhibit the ability of the human immunodeficiency virus (HIV) or other types of retroviruses to multiply in the body.

(Antiretroviral therapy, NCI Dictionary)

The strain is viremic from birth in that all tissues express the AKV retrovirus and copies of the AKV genome are integrated in the mouse genome, which is associated with leukemia development.

(AKR/J Mouse, NCI Thesaurus)

Human autologous T-lymphocytes are isolated and transduced ex vivo with a retrovirus encoding a chimeric immune receptor (CIR) consisting of an antibody fragment against PSMA fused with signaling domains of the T cell.

(Autologous Anti-PSMA Gene-Modified T-Lymphocytes, NCI Thesaurus)

A retrovirus that is associated with leukemia and induces in vitro transformation of certain mouse cells.

(Abelson Murine Leukemia Virus, NCI Thesaurus)