| Health / Medical Topics |
RGD Motif
A consensus tripeptide that is recognized by and for binding to proteins of the integrin family, including many cell adhesion molecules. The one-letter codes for arginine - glycine - aspartic acid. This motif can be found in proteins of the extracellular matrix and it is recognized by different members of the integrin family. The structure of the tenth type III module of fibronectin has shown that the RGD motif lies on a flexible loop. (NCI Thesaurus)
YOU MAY ALSO LIKE
A drug used to treat advanced melanoma that has a mutated (changed) form of a cell protein called BRAF. It is…
A non-phenolic tyrphostin-class tyrosine kinase inhibitor that inhibits epidermal growth factor receptor, affecting cell proliferation and tumor growth in vivo.
A tyrosine kinase inhibitor that selectively inhibits epidermal growth factor receptor, epidermal factor-stimulated HER14 cell proliferation, and tumor growth in vivo. …
A 5-hydroxytryptamine-3 (5-HT3) receptor antagonist with antiemetic activity. RG 12915 binds to and antagonizes the action of serotonin on the 5-HT-3 receptor…
A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of melanoma that has spread to distant…
In cancer, the length of time after primary treatment for a cancer ends that the patient survives without any signs or symptoms…
