Health / Medical Topics

    Ring Finger Domain

    The RING finger is a specialized type of Zn-finger consisting of 40 to 60 residues, which has the consensus sequence CX2CX(9-39)CX(1-3)HX(2-3)C/HX2CX(4-48)CX2C, that binds two atoms of zinc, and is involved in mediating protein-protein interactions. The RING domain mediates the interaction with the appropriate E2 enzyme. Unlike HECT E3 enzymes that form a thiol-ester with ubiquitin, RING fingers likely mediate ubiquitination by facilitating the direct transfer of ubiquitin from E2 enzyme to lysine residues on the target substrate. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A dosing unit equal to the amount of active ingredient(s) contained in a ring.
    A solid composed active and/or inert ingredient(s) of in the shape of a hoop.
    Any doughnut-shaped device.
    A cyclic compound. any compound in which the constituent atoms, or any part of them, form a ring. Used mainly in organic…
    RING-box protein 1 (108 aa, ~12 kDa) is encoded by the human RBX1 gene. This protein plays a role in the modulation…
    An artifact that is due to errors in an individual detector calibration.

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact