| Health / Medical Topics |
RIPK1 wt Allele
Human RIPK1 wild-type allele is located in the vicinity of 6p25.2 and is approximately 37 kb in length. This allele, which encodes receptor-interacting serine/threonine-protein kinase 1 protein, is involved in positive regulation of apoptosis and activation of the transcription factor NF-kappa-B. The RIPK1 gene is down-regulated in mantle cell lymphomas. (NCI Thesaurus)
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