Health / Medical Topics |
RNA Recognition Motif
RNA Binding Domains (RBD) mediate the interaction of RNAs with RNA-binding proteins. RBDs of about 90 amino acids consist of a four-stranded beta sheet adjacent to two alpha helixes. Within RBDs, conserved RNP-1 and RNP-2 motifs on the central beta sheets lie side by side; their side chains contact RNA. (NCI Thesaurus)
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