RNF213/ALK Fusion Gene

A fusion gene that results from a chromosomal translocation t(2;17)(p23;q25) which fuses the first 16 exons of the RNF213 gene with the last ten exons of the ALK gene. This fusion is associated with anaplastic large cell lymphoma. (NCI Thesaurus)

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RNF213 wt Allele

Human RNF213 wild-type allele is located in the vicinity of 17q25.3 and is approximately 135 kb in length. This allele, which encodes…

RNF213 Gene

This gene may be involved in ubiquitination.

RNF20 wt Allele

Human RNF20 wild-type allele is located in the vicinity of 9q22 and is approximately 29 kb in length. This allele, which encodes…

RNF20 Gene

This gene plays a role in polyubiquitination, histone modification and transcriptional regulation.

RNF146 wt Allele

Human RNF146 wild-type allele is located within 6q22.1-q22.33 and is approximately 22 kb in length. This allele, which encodes E3 ubiquitin-protein ligase…

RNF146 Gene

This gene plays a role in both the ubiquitination and degradation of poly-ADP-ribosylated proteins.