Health / Medical Topics |
RNF213/ALK Fusion Protein
A fusion protein (680 aa, ~75 kDa) that is encoded by the RNF213/ALK fusion gene. This protein contains 1172 N-terminal amino acids of protein ALO17 fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein. (NCI Thesaurus)
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A fusion gene that results from a chromosomal translocation t(2;17)(p23;q25) which fuses the first 16 exons of the RNF213 gene with the…
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Human RNF20 wild-type allele is located in the vicinity of 9q22 and is approximately 29 kb in length. This allele, which encodes…
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Human RNF146 wild-type allele is located within 6q22.1-q22.33 and is approximately 22 kb in length. This allele, which encodes E3 ubiquitin-protein ligase…