Health / Medical Topics |
RNF213 wt Allele
Human RNF213 wild-type allele is located in the vicinity of 17q25.3 and is approximately 135 kb in length. This allele, which encodes RING finger protein 213, may play a role in the regulation of protein ubiquitination. A chromosomal translocation t(2;17)(p23;q25) of this gene with the ALK gene is associated with anaplastic large cell lymphoma. (NCI Thesaurus)
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