Health / Medical Topics

    RSF1 wt Allele

    Human RSF1 wild-type allele is located in the vicinity of 11q14.1 and is approximately 155 kb in length. This allele, which encodes remodeling and spacing factor 1 protein, plays a role in transcriptional repression, transcriptional co-activation and nucleosome assembly controlled by the RSF chromatin remodeling complex. The RSF1 gene is overexpressed in high-grade ovarian serous carcinoma. (NCI Thesaurus)




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