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S100 calcium binding protein A9
Pronunciation
Definition 1
A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer. Also called calgranulin B. (NCI Dictionary)
Definition 2
Constitutively expressed in epithelial cells and in macrophages within inflamed tissues by human S100A9 Gene (S100 Family), 114-aa 13-kDa S100 Calcium Binding Protein A9, containing 2 EF-hand calcium-binding motifs, may inhibit protein kinases and interact with intermediate filament components. Altered expression of S100A9 is associated with cystic fibrosis. (NCI Thesaurus)
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