Health / Medical Topics |
SDHC wt Allele
Human SDHC wild-type allele is located in the vicinity of 1q23.3 and is approximately 50 kb in length. This allele, which encodes succinate dehydrogenase cytochrome b560 subunit, mitochondrial protein, plays a role in the regulation of the electron transport chain. Mutation of the gene is associated with both Carney-Stratakis syndrome and hereditary paraganglioma type 3. (NCI Thesaurus)
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