Health / Medical Topics |
SDZ 280-446
A novel semi-synthetic derivative of cyclosporin and a cyclodepsipeptide with chemo-sensitizing activity. SDZ 280-446 is one of the drug resistance-modifying agents that inhibit P-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activities of some drugs in drug-resistant tumor cells. (NCI Thesaurus)
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A question associated with the SDS questionnaire.
Sheehan Disability Scale (SDS) The symptoms have disrupted your work/school work.
Sheehan Disability Scale (SDS) The symptoms have disrupted your social life/leisure activities.
Sheehan Disability Scale (SDS) The symptoms have disrupted your family life/home responsibilities.
Sheehan Disability Scale (SDS) I have not worked/studied at all during the past week for reasons unrelated to the disorder.