| Library / English Dictionary |
SELECTIVITY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The property of being selective
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("selectivity" is a kind of...):
property (a basic or essential attribute shared by all members of a class)
Derivation:
selective (tending to select; characterized by careful choice)
selective (characterized by very careful or fastidious selection)
Context examples:
Less time on the column then translates to narrower peaks in the resulting chromatogram and thence to better selectivity and sensitivity.
(High Performance Liquid Chromatography, NCI Thesaurus)
Deletion of the gene encoding for ICP34.5 provides tumor selectivity and prevents replication in healthy cells.
(Oncolytic Herpes Simplex Virus-1-encoding GM-CSF, NCI Thesaurus)
This lack of selectivity in directing anticancer drugs is the cause of the often devastating side effects that cancer patients experience during chemotherapy treatment.
(Scientists successfully deliver “Trojan horse” catalysts into cancerous tumour cells to destroy them from within, Universities of Granada)
Anti-CD70 fully human monoclonal antibody MDX-1411 selectivity binds to the extracellular domain of CD70, which may induce an antibody-dependent cellular cytotoxicity (ADCC) response against CD70-expressing tumor cells.
(Anti-CD70 Monoclonal Antibody MDX-1411, NCI Thesaurus)
The hydrochloride salt form of apomorphine, a derivative of morphine and non-ergoline dopamine agonist with high selectivity for dopamine D2, D3, D4 and D5 receptors.
(Apomorphine Hydrochloride, NCI Thesaurus)
The researchers also found that the category selectivity of neural activity patterns in the prefrontal cortex was task-dependent.
(How does the brain learn categorization for sounds? The same way it does for images, National Science Foundation)
The platform, combined with high-tech imaging, detects genes and characterizes different kinds of stem cells with greater reliability, selectivity and sensitivity than today's biosensors.
(Better biosensor technology created for stem cells, National Science Foundation)
This agent displays selectivity activity towards both hypoxic solid tumors, which exhibits higher expression of cytochrome P450 reductase, and well-oxygenated malignant cells that overexpress the bioreductive enzyme NQO1 (NAD(P)H: quinone oxidoreductase).
(Apaziquone, NCI Thesaurus)
These chemical elements are requisites for molecular structure, and they determine both the reactivity and selectivity of nanoparticles.
(Nanoparticle Chemical Characterization, NCI Thesaurus)
While vaccinia displays a natural tumor cell tropism, deletion of the thymidine kinase gene increases the tumor selectivity of vaccinia by limiting viral replication to transformed cells. hGM-CSF expression by this agent may help recruit antigen processing cells (APCs), such as denritic cells and macrophages, to virally infected tumor cells, initiating a systemic antitumoral immune response.
(Pexastimogene-devacirepvec, NCI Thesaurus)
