Health / Medical Topics |
SET wt Allele
Human SET wild-type allele is located within 9q34 and is approximately 12 kb in length. This allele, which encodes protein SET, plays a role in histone binding, nucleosome assembly, transcription and negative regulation of apoptosis. Translocation of the SET gene is associated with acute undifferentiated leukemia. (NCI Thesaurus)
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