SGPT (ALT)

Definition 1

Activity measured as a test of liver function, human Glutamic-Pyruvate Transaminases (Alanine Aminotransferase Family) are pyridoxal phosphate-dependent enzymes involved in cellular nitrogen metabolism, amino acid metabolism, and liver gluconeogenesis. Glutamic Pyruvic Transaminases mediate conversion of major intermediate metabolites, catalyzing reversible transamination between alanine and alpha-ketoglutarate to form pyruvate and glutamate. (NCI Thesaurus)

Definition 2

An enzyme found in the liver and other tissues. A high level of serum glutamate pyruvate transaminase released into the blood may be a sign of liver damage, cancer, or other diseases. (NCI Dictionary)

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